Téléchargez le livre : Survival Analysis with Correlated Endpoints

Survival Analysis with Correlated Endpoints

Joint Frailty-Copula Models de

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Éditeur :

Springer


Collection :

SpringerBriefs in Statistics

Paru le : 2019-03-25

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Description

This book introduces readers to advanced statistical methods for analyzing survival data involving correlated endpoints. In particular, it describes statistical methods for applying Cox regression to two correlated endpoints by accounting for dependence between the endpoints with the aid of copulas. The practical advantages of employing copula-based models in medical research are explained on the basis of case studies.
In addition, the book focuses on clustered survival data, especially data arising from meta-analysis and multicenter analysis. Consequently, the statistical approaches presented here employ a frailty term for heterogeneity modeling. This brings the joint frailty-copula model, which incorporates a frailty term and a copula, into a statistical model. The book also discusses advanced techniques for dealing with high-dimensional gene expressions and developing personalized dynamic prediction tools under the joint frailty-copula model.
To help readers apply the statistical methods to real-world data, the book provides case studies using the authors’ original R software package (freely available in CRAN). The emphasis is on clinical survival data, involving time-to-tumor progression and overall survival, collected on cancer patients. Hence, the book offers an essential reference guide for medical statisticians and provides researchers with advanced, innovative statistical tools. The book also provides a concise introduction to basic multivariate survival models.
Pages
118 pages
Collection
SpringerBriefs in Statistics
Parution
2019-03-25
Marque
Springer
EAN papier
9789811335150
EAN PDF
9789811335167
Informations sur l'ebook
Nombre pages copiables
1
Nombre pages imprimables
11
Taille du fichier
4157 Ko
Prix
63,29 €
EAN EPUB
9789811335167
Informations sur l'ebook
Nombre pages copiables
1
Nombre pages imprimables
11
Taille du fichier
9923 Ko
Prix
63,29 €

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