A Phenomenological Mathematical Modelling Framework for the Degradation of Bioresorbable Composites

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Éditeur :

Springer


Collection :

Springer Theses

Paru le : 2019-04-05

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Description


This book presents a generalised computational model for the degradation of resorbable composites, using analytic expressions to represent the interwoven phenomena present during degradation. It then combines this modelling framework with a comprehensive database of quantitative degradation data mined from existing literature and from novel experiments, to provide new insights into the interrelated factors controlling degradation.
Resorbable composites made of biodegradable polyesters and calcium-based ceramics have significant therapeutic potential as tissue engineering scaffolds, as temporary implants and as drug-loaded matrices for controlled release. However, their degradation is complex and the rate of resorption depends on multiple connected factors such as the shape and size of the device, polymer chemistry and molecular weight, particle phase, size, volume fraction, distribution and pH-dependent dissolution properties. Understanding and ultimately predicting the degradation of resorbable composites is of central importance if we are to fully unlock the promise of these materials.
Pages
325 pages
Collection
Springer Theses
Parution
2019-04-05
Marque
Springer
EAN papier
9783030049898
EAN PDF
9783030049904

Informations sur l'ebook
Nombre pages copiables
3
Nombre pages imprimables
32
Taille du fichier
15636 Ko
Prix
147,69 €
EAN EPUB
9783030049904

Informations sur l'ebook
Nombre pages copiables
3
Nombre pages imprimables
32
Taille du fichier
29542 Ko
Prix
147,69 €