Téléchargez le livre : Gasotransmitters in Organ Transplantation

Gasotransmitters in Organ Transplantation

A New Era in Transplant Medicine de

Éditeur :

Springer


Paru le : 2024-03-30

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Description

This book covers recent pre-clinical and clinical developments in gasotransmitters (nitric oxide, carbon monoxide and hydrogen sulfide) in all transplantable solid organs – kidney, heart, lung, liver, pancreas and intestine. Gasotransmitters are a class of small endogenously produced gaseous signaling molecules that play important roles in cellular homeostasis and impact physiological and pathophysiological situations. Recently, these gasotransmitters have emerged as potent cytoprotective mediators, possessing therapeutic properties that enable them exhibit their intracellular signaling functions. Hence, alterations in their physiological levels have been associated with various pathologies including cold ischemia-reperfusion injury (IRI) in organ transplantation.


In the context of organ transplantation, a novel therapeutic strategy that is being investigated involves administration of these gasotransmitters to the organ donor or recipient before or after transplantation, or supplementation of standard preservation solution with gasotransmitters during organ graft preservation to mitigate transplant-induced IRI. The book is divided into three parts for easier access: Hydrogen Sulfide in Organ Transplantation, Carbon Monoxide in Organ Transplantation, and Nitric Oxide in Organ Transplantation.


The proposed book presents recent advances in organ graft protection mediated by gasotransmitters against warm and cold IRI in preclinical models of organ transplantation and some selected clinical cases, and seeks to lay the foundation for future clinical applications of these gases. The book is topical and timely, and will serve as a good resource for both educational and didactic purposes in transplant patient care and other aspects of clinical medicine.
Pages
303 pages
Collection
n.c
Parution
2024-03-30
Marque
Springer
EAN papier
9783031480669
EAN PDF
9783031480676
Informations sur l'ebook
Nombre pages copiables
3
Nombre pages imprimables
30
Taille du fichier
11110 Ko
Prix
137,14 €
EAN EPUB
9783031480676
Informations sur l'ebook
Nombre pages copiables
3
Nombre pages imprimables
30
Taille du fichier
4844 Ko
Prix
137,14 €

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