Téléchargez le livre : Proteostasis

Proteostasis

Investigating Molecular Dynamics in Neurodegenerative Disorders de

Éditeur :

Springer


Paru le : 2025-07-12

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Description

This book explores the role of proteostasis in neurodegenerative disorders, focusing on protein homeostasis in long-lived, nondividing cells like neurons. It examines how disruptions in proteostasis, influenced by factors such as oxidative stress, aging, and environmental stress, contribute to diseases like Alzheimer’s, Parkinson’s, and amyotrophic lateral sclerosis. The book begins with an overview of the epidemiology and management of neurodegenerative diseases. Subsequent chapters delve into the mechanisms governing proteostasis, highlighting the ubiquitin-proteasome system, molecular chaperones, and co-chaperones in protein folding and degradation. It further explores how impairments in these pathways contribute to neuroinflammation and disease progression. By providing insights into these cellular processes, the book aims to enhance understanding and support the development of potential therapeutic strategies.
Pages
429 pages
Collection
n.c
Parution
2025-07-12
Marque
Springer
EAN papier
9789819662012
EAN PDF
9789819662029
Informations sur l'ebook
Nombre pages copiables
4
Nombre pages imprimables
42
Taille du fichier
17193 Ko
Prix
241,59 €
EAN EPUB
9789819662029
Informations sur l'ebook
Nombre pages copiables
4
Nombre pages imprimables
42
Taille du fichier
30259 Ko
Prix
241,59 €

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